Laurberg T, Lyngholm CD, Christiansen P, Alsner J, Overgaard J.Overall survival according to type of surgery in young (≤40years) early breast cancer patients: a systematic meta‐analysis comparing breast‐conserving surgery versus mastectomy. Family history and risk of breast cancer: an analysis accounting for family structure. Brewer HR, Jones ME, Schoemaker MJ, Ashworth A, Swerdlow AJ.Younger women with breast carcinoma have a poorer prognosis than older women.Ĭancer. Chung M, Chang HR, Bland KI, Wanebo HJ.Do younger female breast cancer patients have a poorer prognosis? Results from a population-based survival analysis. ![]() Chia KS, Du WB, Sankaranarayanan R, Sankila R, Wang H, Lee J, et al.Elevated breast cancer mortality in young women (3.0.CO 2-Y Gnerlich J, Deshpande A, Jeffe D, Sweet A, White N, Margenthaler J.Supervised risk predictor of breast cancer based on intrinsic subtypes. Parker JS, Mullins M, Cheang MC, Leung S, Voduc D, Vickery T, et al.Is Breast Cancer the Same Disease in Asian and Western Countries? World J Surg. Leong SP, Shen ZZ, Liu TJ, Agarwal G, Tajima T, Paik NS, et al.The prognosis is worse in these patients, and prognostic factors and pathological subtypes should be taken into consideration when making treatment decisions. Median was 30☑.8 (27.4–32.5) months.Ĭonclusion: Breast cancer patients under the age of 40 years are highly heterogeneous and are a complex patient group. ![]() Overall, survival of 1, 3 and 5 years was 88%, 74% and 65%, respectively. 95% confidence interval = 1.037–53.928, p=0.045), lymphovascular invasion presence (hazard ratio = 0.127, 95% confidence interval = 0.016–1.025, p=0.005) and curative radiotherapy doses (hazard ratio = 185.976, 95% confidence interval = 5.342–6474.1, p=0.004) as independent prognostic factors for disease-free survival. In multivariate Cox regression analysis, we found breast-conserving surgery type (hazard ratio = 6.104. No prognostic factors were found in the multivariate Cox regression analysis for overall survival. Results: First-degree relatives with breast cancer history ( p=0.028), oestrogen receptor positivity ( p=0.012) and progesterone receptor positivity ( p=0.017) were associated with overall survival. Material and methods: A total of 80 patients who were receiving radiotherapy and/or chemotherapy treatment for breast cancer (<40 years old) were included in the study. Objective: This retrospective research aimed to evaluate the results of treatment outcome and clinicopathological features of breast cancer patients under 40 years old.
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